WHAT ARE THE BIGGEST BENEFITS?

On-time decision making

Get live data throughout your process and see what improves product quality in real-time. Gain insight from data-driven feedback control with greater product consistency and fewer batch reworks and rejects.

Multieye2 Implement Quality by Design

SEE INSIDE YOUR PROCESS

Implement Quality by Design

Monitor the evolution of your product processing with Multieye2. Evaluate your critical quality attributes continuously. Respond on time to deviations to improve batch quality while reducing the burden of time and cost on laboratory analysis.

AUTOMATE FOR DATA-DRIVEN PRODUCTION

Progress to Pharma 4.0

Use Multieye2 to monitor your process remotely. Automatically adjust process parameters using sensor data in real-time to accelerate development and move to the next industrial revolution.

Multieye2 progress to pharma 4.0
Multieye2 characterise process transfer

RAPID, SUCCESSFUL SCALE-UP

Fully characterise your process for transfer

Capture the impact of your critical process parameters in real-time and gain control of your critical quality attributes. Track moisture content, API concentration, or density pre and post-transfer and simply demonstrate the equivalence of product scale-up.

Technical Specifications


Measurement

Spectral Range 1050 – 2100 nm 

Number of channels

Single Channel Unit
Four Channel Unit (1-4)
Spectral resolution
6 nm FWHM
Data acquisition timeFrom 1 ms, configurable and sample/process
dependent, typically 100-150 ms
Spectrometer typeTransmissions diffraction grating with TE-cooled InGaAs CCD array detector
Dynamic range 6000:1
S/N 2500:1
Probes
Non-product contact as default, contact options also available
 
Spot Size
Configurable based on probe selection
 

Probe connectors

SC or SMA
Communications
Plug & Play USB
OPC Support

 

Physical

Dimensions
(h) 95 x (w) 385 x (d) 245 mm
 
Power
110VAC @ 50HZ / 230 VAC @ 50HZ
 
Weight
Approximately 9 kg
 

Application Notes

Roller compacted ribbon and granule properties

The Use of PAT and Off-line Methods for Monitoring of Roller Compacted Ribbon and Granule Properties with a View to Continuous Processing

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PARTICLES

NIR Spectroscopy for Real-Time, In-Line Measurement of API Concentration in a Continuous Blending Process.

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Technology

Monitoring Moisture Content in Fluid Bed Drying with NIR Spectroscopy 

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Noisy Spectral Data Application Note for Multieye2

Near-infrared monitoring of roller-compacted ribbon density: Investigating sources of variation contributing to noisy spectral data

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Improved process understanding in fluid bed granulation

NIR Spectroscopy for Real-Time, In-Line Measurement of Moisture Content for Improved Process Understanding in Fluid Bed Granulation

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WHAT ARE THE BIGGEST BENEFITS?

End-to-end integration support

With Innopharma Technology’s team of mechanical, electronic, and application engineers, we have extensive experience collaborating with process experts to achieve successful measurement and process integration solutions from the equipment level with Multieye2, to integration with automated software platforms, such as SmartX, for advanced process control.

Multieye2 avail the trial facility

GAIN INSIGHT INTO YOUR MATERIAL

Avail of our trial facility

For peace of mind, we invite customers to undertake a trial of their material at our Ireland application lab (with optional customer attendance), where we offer sample analysis with Multieye2. Trials can also replicate real-world conditions with a wide range of processing equipment available to offer assurance that Multieye2 can meet their analytical requirements

LET’S START A CONVERSATION

Putting NIR technology to work

We at Innopharma Technology work with industry scientists and engineers to understand the challenges they face, and the risks when embedding new technology. Embedding NIR technology into your process provides a competitive edge, and Innopharma Technology aims to help facilities get to market faster, improve process understanding and achieve higher standards of quality by offering versatile solutions suited to their needs.

Multieye2 putting NIR technology to work
Multieye2 Chemometric model development service

ADD VALUE FROM DAY-1

Chemometric model development

We help customers unlock the full potential of Multieye2 by offering a number of services. On-site training ensures users are confident with the technology, while top-notch customer support and extended maintenance contracts ensure you’re never more than a phone call away from help when needed. Chemometric model development offers an efficient and traceable method for system calibration/verification, and our IQ OQ template streamlines the qualification process, with optional on-site execution by our own expert engineers.

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Testimonials

The Eyecon is outstanding in measuring in-process particle size during the granulation and particle coating processes. We also integrated this technology into our control systems, as part of a Process Analytical Technology package desired by some of our clients.

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Ed Godek | Process Technology Manager | Glatt Air Techniques, Inc.

While using the Multieye to measure roller compaction ribbons, we observed an excellent correlation between the NIR spectra and off-line density results.

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Abina Crean | Lecturer in Pharmaceutics | University College Cork

Eyecon₂ with its automated high-speed image analysis is implemented to accurately predict the process end-point with fast objective PSD data, supported by particle images, to significantly improve process optimisation and control.

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Thomas Hoffmeir | Head of Business Unit - Process Technology Pharma | Glatt GmbH

Using the Multieye we have the capability to beautifully monitor the moisture trend in real-time, during the liquid addition and drying process in a fluid bed granulation process.

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Denisio Togashi | Post-Doctoral Researcher | Dublin Institute of Technology

More and more high-end Chinese pharmaceutical manufacturers are aware of and actively seeking to implement QbD principals into their manufacturing processes. Implementation of Eyecon₂ optimises FBP design and subsequently enables increased process understanding.

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Arthur Rong | Vice Manager - Oral Solid Dosage | Austar

Before we had any PAT tools, the process was like a black box to us. We put something in and get something out without knowing what happened inside. Now, we have an ‘Eye’ to look inside that black box and see what’s going on in there.

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Deron HE | General Manager - Smart Manufacturing | Chanse Technology (Jiangsu) Inc.

Organisations we have worked with…

Glatt
TU DUBLIN
CHANSE
AUSTAR
purdue 
RUTGERS UNIVERSITY
servier