WHAT ARE THE BIGGEST BENEFITS?

Reduced cycle time, increased yields 

  • Eyecon2TM  is built to the rigorous standards of the pharmaceutical industry but can be used anywhere powders and bulk solids flow, for example in the food, chemical, agricultural, cosmetics and veterinary industries. 
  • Tried and tested through installations around the world on Fluidised Bed Coating (e.g Wurster) Fluidised bed Granulation/Drying, Twin Screw Granulation, Dry Granulation/Roller Compaction, Extrusion, Spheronisation, Milling, Blending, and product transfer process equipment.
  • Uses direct imaging processed in real-time, with ellipses fitted to each particles boundary, shape and size reported back, highlighting variations. 
  • Continuous monitoring of a processes critical quality attributes (CQAs) delivers sufficient understanding to devise a data-driven control strategy. 
  • Can be used both in-line and at-line for batch and continuous processes
EYECON2

 

to know more about the Eyecon2, please fill in the form below

 

Get In Touch

Tech Specs

Eyecon2 Tech Specs


Measurement
Size Range50 - 5500 μm
Principle Measurement Method (non-product contact)Direct Imaging
Size Measurement DataD10, D25, D50, D75, D90 in numeric and volumetric with Mean and Median values all trended in real time with live histogram and S-curve results. Includes process deviation alarm. 
Shape Measurement DataEccentricity Average, Eccentricity RSD, Range 0-1
Exportable DataPDF report of recording session, CSV file with data on every image analysed with full PSD from D5-D95, captured images exportable as JPEG
Data ProcessingEyePASSTM real time particle analysis software installed on a dedicated IPC/PC/Laptop with Windows 10
Measurement Time ~ 5 seconds per image
Material Speed (max.)≈ 10 m/sec
Imaging
Illumination source12x3 High intensity, low energy R,G,B LEDs
Image Area11.25 mm x 11.25 mm
Pixel Size5.5 μm x 5.5 μm
Resolution2046 px x 2046 px
Shutter Speed25 fps
SensorCMOS
Physical
Dimensions & WeightEyecon2250 x 128 x 132 mm (4 kg)

Connection Hub254 x 170 x 57 mm (1.2 kg)

Eyecon2 inc. Automated Benchtop Stage300 x 190 x 480 mm (7.8 kg)
Power230VAC @ 50HZ / 110VAC @ 60HZ 
Casing Materials 304 Stainless steel, Glass window, Silicon gaskets 
Connection CableFrom Eyecon2 to Connections Hub via Speedcon quick-release power & data cable, available in lengths up to 25 m. From Connections Hub to IPC/Laptop via USB 
Software
Eyepass logo
GMPEyePASS is both 21 CFR part 11 & GAMP5 Compliant
Communications

EyePASS is Open Platform Communications compatible with OPC UA & OPC DA 3

Conformance & Certifications
CE Marking    
CE LOGO
EU declaration of conformity
ATEX Certified    
ATEX logo
The Eyecon2 is suitable for ATEX zones 2/22, IP65.
IECX Certs    
IECX Logo
International Electrotechnical Commission Explosive Standards certification available upon request

 

Downloads

Eyecon2 White-Papers

eyecon

Methods of Particle Size Determination – A Review

Download

Automated Control Strategy

An Automated Control Strategy for Wurster Coating to Reduce Dissolution Variability due to Raw Material Variation

Download

particles

Particle Size Analysis of 2 – 5 mm Particles of Varying Colour from Coating and Granulation Processes using Process Analytical Technology

Download

Eyecon

A Guide to D-values in Pharmaceutical Particle Characterisation

Download

 

graph

The use of Real-Time At-Line Particle Size Measurement on a Pelletization  Process for Accurate End-Point Prediction

Download

P1030293

Unique Advantages of Process Analytical Technology in Twin-Screw Granulation

Download

Eyecon

Real-Time In-Line Monitoring of the Impact of Process Parameter Changes on Critical Quality Attributes in Fluid Bed Granulation using Process Analytical Technology

Download

Particle

Real-Time Prediction of Polymer-Coated Multiparticulate Dissolution using Process Analytical Technology

Download

PAT

Implementation of PAT for In-Line Monitoring of a Milling Process During DoE for Continuous Processing

Download

 
 
   
 
 
 

Testimonials

The Eyecon is outstanding in measuring in-process particle size during the granulation and particle coating processes. We also integrated this technology into our control systems, as part of a Process Analytical Technology package desired by some of our clients.

testimonial-img

Ed Godek | Process Technology Manager | Glatt Air Techniques, Inc.

While using the Multieye to measure roller compaction ribbons, we observed an excellent correlation between the NIR spectra and off-line density results.

testimonial-img

Abina Crean | Lecturer in Pharmaceutics | University College Cork

Eyecon₂ with its automated high-speed image analysis is implemented to accurately predict the process end-point with fast objective PSD data, supported by particle images, to significantly improve process optimisation and control.

testimonial-img

Thomas Hoffmeir | Head of Business Unit - Process Technology Pharma | Glatt GmbH

Using the Multieye we have the capability to beautifully monitor the moisture trend in real-time, during the liquid addition and drying process in a fluid bed granulation process.

testimonial-img

Denisio Togashi | Post-Doctoral Researcher | Dublin Institute of Technology

More and more high-end Chinese pharmaceutical manufacturers are aware of and actively seeking to implement QbD principals into their manufacturing processes. Implementation of Eyecon₂ optimises FBP design and subsequently enables increased process understanding.

testimonial-img

Arthur Rong | Vice Manager - Oral Solid Dosage | Austar

Before we had any PAT tools, the process was like a black box to us. We put something in and get something out without knowing what happened inside. Now, we have an ‘Eye’ to look inside that black box and see what’s going on in there.

testimonial-img

Deron HE | General Manager - Smart Manufacturing | Chanse Technology (Jiangsu) Inc.

Organisations we have worked with…

Glatt
TU DUBLIN
CHANSE
AUSTAR
purdue 
RUTGERS UNIVERSITY
servier