Unique Advantages of Process Analytical Technology in Twin-Screw Granulation 

 

Twin-Screw Granulation (TSG) has emerged as a popular continuous manufacturing technology for consistent, repeatable high-quality production of both standard and complex dosage forms. This application note presents parts of a wide-ranging experimental plan involving the building of a data-driven process map for twin-screw granulation using real-time particle size measurement. The experiments presented here demonstrate both how PAT can dramatically decrease the time required to define, execute and analyse the data from a DoE, and how it can provide information which is not plausible from traditional off-line analysis methods.

 

Download Now

Thank you for your interest in our whitepapers. Your download should start automatically.

Organisations we have worked with…

Glatt
TU DUBLIN
CHANSE
AUSTAR
purdue 
RUTGERS UNIVERSITY
FDA