The use of Real-Time At-Line Particle Size Measurement on a Pelletization  Process for Accurate End-Point Prediction

The direct pelletization process is a fast and flexible operation with the potential to produce high quality particles appropriate for sophisticated oral solid dose formulations where a narrow particle size distribution is required. Traditional methods are too slow or subjective and therefore may be an unacceptable risk for use as an in-process control in a control strategy. An at-line direct imaging method with automated high-speed image analysis can be practically used during processing to accurately predict the process end-point with fast objective PSD data, supported by particle images, to significantly improve process optimisation and control.

 

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Organisations we have worked with…

Glatt
TU DUBLIN
CHANSE
AUSTAR
purdue 
RUTGERS UNIVERSITY
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